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Kara Fitzgerald

Kara Fitzgerald

Functional Medicine, Epigenetic Age Researcher

ND (Naturopathic Doctor)

You can reverse your biological age in weeks by targeting DNA methylation through food and lifestyle — your epigenome is not fixed fate.

EpigeneticsDna MethylationFunctional MedicineBiological Age

Controversy Notes

Functional medicine framing; commercial program tie-in.

Episodes

20 episodes
How He Reversed MS & Beat a Stroke | Montel Williams

How He Reversed MS & Beat a Stroke | Montel Williams

May 15 (3mo ago)

Inflammation is your nemesis. Anything you can do to reduce inflammation in your life you should attempt to do.

multiple-sclerosisinflammationmitochondrial-healthmitoqautoimmunity
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Why Bone Loss Accelerates With Aging The Gut–Bone Connection

Why Bone Loss Accelerates With Aging The Gut–Bone Connection

Feb 24 (5mo ago)

Osteoclastogenesis, so the development of those bone breaking down cells is actually an inflammatory process. It uses the same inflammatory signals that drive maturation of macrophages.

bone-healthosteoporosisosteopeniagut-bone-axisinflammation
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Epstein Files: A Functional Medicine Response

Epstein Files: A Functional Medicine Response

Feb 12 (6mo ago)

I feel disregulated by the way he parses data and the um there's kind of an abrasiveness to the way he talks about science that I find off-putting.

epstein-filespeter-attiadeepak-chopramedical-accountabilitytrauma-informed-care
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Why Aging Is Not a Fat Problem — A Muscle Centric Approach to Longevity

Why Aging Is Not a Fat Problem — A Muscle Centric Approach to Longevity

Jan 20 (6mo ago)

I think that obesity is in part a symptom of unhealthy muscle and we're looking at body fat percentages as that meaningful marker.

obesity-muscle-linkintramuscular-adipose-tissuemetabolic-syndromemuscle-qualityanabolic-resistance
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Platelet Derived Exosomes in Aesthetics Data, Safety, and Real World Use Cases

Platelet Derived Exosomes in Aesthetics Data, Safety, and Real World Use Cases

Jan 6 (7mo ago)

The exosome actually goes into the cell and then it leaves. So, it's very polite.

platelet-derived-exosomesregenerative-medicineskin-rejuvenationhair-growthexosome-penetration
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The Oral Microbiome The Hidden Biomarker Driving Aging, Fertility & Systemic Inflammation

The Oral Microbiome The Hidden Biomarker Driving Aging, Fertility & Systemic Inflammation

Dec 16, 2025 (8mo ago)

We cannot treat the gut without treating the mouth and vice versa. I mean the mouth is the gut. That's the biggest take-home here.

oral-microbiomeleaky-gumsgingival-permeabilitysystemic-inflammationmouth-breathing
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The Hidden Immune Signal Accelerating Aging & the Beta Glucan That Fixes It  Bob Rountree and Chris

The Hidden Immune Signal Accelerating Aging & the Beta Glucan That Fixes It Bob Rountree and Chris

Dec 2, 2025 (8mo ago)

It's like the old guy sitting on the park bench taking a nap, except he's throwing poison darts.

beta-glucan-structureimmune-trainingcancer-clinical-trialsvaccine-responseimmunosenescence
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From Hot Flashes to Healthspan The FxMed Guide to Hormones and Longevity

From Hot Flashes to Healthspan The FxMed Guide to Hormones and Longevity

Nov 18, 2025 (8mo ago)

Melatonin is a stronger antioxidant than glutathione.

ovarian-mitochondriahormone-synthesismitchondrial-healthperimenopause-symptomsocular-migraines
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Guide to Building a Sustainable Concierge Longevity Practice

Guide to Building a Sustainable Concierge Longevity Practice

Nov 4, 2025 (9mo ago)

I implemented all of the pillars of lifestyle medicine and I felt a 180 in how I was feeling. A 180 in my lab work. My cholesterol improved. my blood pressure improved. my symptoms of anxiety, irritability, headaches, en

burnoutlifestyle-medicine-transitionconcierge-practice-setuppricing-strategysolo-practice-management
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Reversing Aging: Screening, Wearables & What To Do Now

Reversing Aging: Screening, Wearables & What To Do Now

Oct 21, 2025 (9mo ago)

I'm not a big fan of immortality as the concept, right? I think in fact, if you take out death from the human life cycle, I mean, we're not going to be humans.

longevity-forecastmini-liveshealthspan-extension-choicesimmortalityage-related-diseases
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Aging & Hair Loss Explained: OS-01’s Science-Backed Approach

Aging & Hair Loss Explained: OS-01’s Science-Backed Approach

Sep 25, 2025 (10mo ago)

We've lost 50% of our hair before we realize that our hair is thinning and there's a huge emotional toll in that. It's very anxietyprovoking.

cellular-senescenceos-01-peptidehair-loss-mechanismsenescent-cells-hair-folliclesminoxidil-comparison
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The Bile Acid Imbalance Accelerating Aging: How to Detect ​& Fix It

The Bile Acid Imbalance Accelerating Aging: How to Detect ​& Fix It

Sep 25, 2025 (10mo ago)

inflammation is a biological phenomenon that defies simple definition.

dysbiosis-redefinitionmicrobiome-ecosysteminflammation-spectrumimmunometabolismbutyrate-anaerobic-gut
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Why Functional Medicine Is the Future of Longevity

Why Functional Medicine Is the Future of Longevity

Sep 4, 2025 (11mo ago)

Functional medicine is longevity medicine. You know, if you're walking around the matrix and looking at all the imbalances that can occur, it's amazing how that overlaps with the quote pillars of aging.

functional-medicinelongevitybiological-age-clocksdna-methylationhorvath-clock
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Why Centenarians Are Defying Science: Secrets to Living 100+

Why Centenarians Are Defying Science: Secrets to Living 100+

Aug 19, 2025 (11mo ago)

the biological age and the chronological age are not the same and understanding that gave me this view that if that's so there's something that we can do about it.

biological-agecentenariansgenetics-longevityhdl-cholesterolcetp
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The Science-Backed Bitter Compound That Mimics GLP-1 (No Injections Needed!) EAT LESS. FEEL FULL.

The Science-Backed Bitter Compound That Mimics GLP-1 (No Injections Needed!) EAT LESS. FEEL FULL.

Aug 5, 2025 (1y ago)

They mapped the whole of our bitter taste receptors right down through the intestinal tract. Now, that hasn't been done before.

bitter-taste-receptorsgut-brain-axisglp-1cckpyy
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10 Year Anniversary: What I Learned After 200+ Conversations with the Best Minds in FxMed

10 Year Anniversary: What I Learned After 200+ Conversations with the Best Minds in FxMed

Jul 24, 2025 (1y ago)

changing the medical paradigm you know changing this disease trajectory that we're on the you know just the breakdown of health the the the compromise of health span and lifespan uh it's an all hands on deck activity

functional-medicinelongevity-medicineepigeneticsdna-methylationmethylation-diet
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Dead Mitochondria Might Be Fueling Cardiovascular Aging — Here’s The Fix

Dead Mitochondria Might Be Fueling Cardiovascular Aging — Here’s The Fix

Jul 8, 2025 (1y ago)

30% of all global death are actually because of heart diseases.

heart-diseasemitochondriaagingurolithin-amitophagy
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Why Human-Centered AI Is the Future of Medicine & Mental Wellness

Why Human-Centered AI Is the Future of Medicine & Mental Wellness

Jun 24, 2025 (1y ago)

It turns out only 7% of how we communicate is in the choice of words we use. 93% is non-verbal.

emotion-aiempathy-crisishuman-centric-aimental-health-aiwearable-integration
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Legal Pitfalls That Could Destroy Your Practice & How to Avoid Them

Legal Pitfalls That Could Destroy Your Practice & How to Avoid Them

Jun 10, 2025 (1y ago)

It's usually not your patient that brings a complaint or does a lawsuit. it's their spouse who's never really fully on board in the beginning or their adult children or sometimes their estate.

functional-medicine-legal-risksconsent-formstelemedicine-licensesscope-of-practicehipaa-compliance
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Why You’re Aging Faster Than You Think & How to Slow It

Why You’re Aging Faster Than You Think & How to Slow It

May 20, 2025 (1y ago)

We think of biological aging as the progressive loss of integrity and resilience capacity in cells, tissues and organs that accumulates as we get older, ultimately makes us sick and kills us.

biological-aging-definitionassets-of-agingmeasuring-agingdunedin-longitudinal-studydunedinpace-epigenetic-clock
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