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Episode
Halle Berry: Why Women Are Being Failed at Menopause
~56 min
Episode Brief·YouTube

Halle Berry: Why Women Are Being Failed at Menopause

Mark Hyman
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TL;DR

The four things you'd lose by not watching

4 items

TL;DR

The four things you'd lose by not watching

4 items
1

Menopause is a severely neglected area in medicine, with 60 million American women suffering unnecessarily due to lack of education among healthcare providers and a prevailing societal acceptance of women's suffering.

2

Halle Berry's personal misdiagnosis of herpes, which turned out to be severe vaginal dryness from perimenopause, highlights the widespread ignorance and misdiagnosis of menopausal symptoms, even among top doctors.

3

The FDA recently lifted the black box warning on hormone replacement therapy (HRT), but the stigma from a flawed 2002 study (Women's Health Initiative) persists, making women hesitant to adopt bioidentical hormones which are safer and more effective.

4

A holistic approach to menopause, including lifestyle changes (diet, exercise, stress management, sleep), nutritional support, and personalized bioidentical hormone therapy, is crucial for managing symptoms and preventing long-term health issues like Alzheimer's and osteoporosis.

Protocols

Concrete recipes — what, when, how much, and why

5 items

Personalized Bioidentical Hormone Replacement Therapy (BHRT)

WhatUsing hormones that are chemically identical to those naturally produced by the body (estrogen, progesterone, testosterone) to alleviate menopausal symptoms and prevent long-term health issues.
WhenIdeally, within a therapeutic window right after menopause for maximum benefit in preventing conditions like Alzheimer's and osteoporosis.
DoseLowest possible dose to achieve benefits, personalized to individual needs. Delivery methods include creams, drops, lozenges, ideally topical rather than oral.
For whomWomen experiencing menopausal symptoms, particularly those seeking to prevent long-term health issues like Alzheimer's and osteoporosis. Requires testing to determine individual hormonal needs.
WhyBioidentical hormones are safer and more effective than synthetic alternatives (like Premarin and Provera) as they don't carry the same risks of inflammation, weight gain, or depression. They can restore libido, drive, and overall well-being.
CaveatsRequires careful testing and personalization by a knowledgeable physician. Overloading with too much testosterone can have adverse effects. Most physicians are not trained in this area, necessitating specialized care or compounding pharmacies.

The discussion strongly advocates for personalized bioidentical hormone replacement therapy (BHRT) as a crucial intervention for menopausal women. Unlike older synthetic hormones like Premarin (pregnant mare's urine) and Provera (synthetic progesterone), which are associated with negative side effects such as increased inflammation, high triglycerides, weight gain, facial hair, and depression, bioidentical hormones are chemically identical to the body's natural hormones. This makes them safer and more effective. The speaker emphasizes that BHRT should be highly personalized, using the lowest effective dose and often applied topically rather than orally. The timing is also critical, with a 'therapeutic window' immediately after menopause being ideal for preventing long-term issues like Alzheimer's and osteoporosis. However, a significant challenge is the lack of physician training in BHRT, often requiring doctors to work with compounding pharmacies to create custom formulations.

Mechanism

Bioidentical hormones replace declining natural hormone levels, restoring physiological balance. Unlike synthetic hormones, they are recognized and processed by the body in the same way as endogenous hormones, minimizing adverse reactions. For example, testosterone can restore libido and energy, while estrogen and progesterone support bone density and brain health.

Personal experience

Halle Berry shares her personal experience with testosterone, initially hesitant due to fears of growing a mustache, but found it transformative. She states, "I got my libido back, and I also got my drive back. There was a certain period of time when I felt very depressed, and I didn't even wanna get out of bed. ... But when I started taking a little bit of testosterone with my estrogen and my progesterone, I got my drive back."

But the bioidentical ones don't do that. So can you talk about the kinds of symptoms that women suffer from?

Also said
“And the only way to know what's going on is you've gotta test. You've gotta measure what's going on.”— Emphasizes the importance of testing for personalized treatment.
“The key to hormone replacement therapy is it's gotta be personalized. It's it's not like a one size fits all.”— Reinforces the need for individualized approaches.
“And so, you know, as a doctor, I had to kind of figure out how to use compounding pharmacies and create the right formulas.”— Highlights the challenge for doctors in prescribing BHRT due to lack of standard formulations.

Clitoral Testosterone Drops

WhatA localized application of testosterone drops directly to the clitoral area.
WhenApplied every night.
DoseTwo drops every night.
For whomWomen seeking to improve libido and sexual function during menopause.
WhyProvides profound benefits for sexual health and libido without the full systemic effects of oral or generalized testosterone, minimizing potential adverse effects.
CaveatsRequires careful prescription and monitoring by a knowledgeable physician due to the lack of FDA-approved formulations for women and the need to avoid overloading the system.

Dr. Hyman discusses clitoral testosterone drops as an innovative and effective method for women to address sexual health concerns during menopause. He explains that this localized application, typically two drops every night, offers 'profound benefits' without the full systemic effects that might come from other forms of testosterone. This approach is particularly valuable because there are very few FDA-approved testosterone preparations specifically for women, forcing doctors to use compounding pharmacies to create these specialized formulas. The success of these drops is evident, according to Dr. Hyman, by the high demand for refills from his patients.

Mechanism

Local application allows for targeted absorption and action of testosterone in the clitoral area, enhancing sensitivity and libido. By avoiding systemic absorption, it reduces the risk of side effects associated with higher circulating testosterone levels.

And, you know, one of the things I came upon was using clitoral testosterone drops that you apply two drops every night, and it has profound benefits. And I know this because women keep calling for refills.

Also said
“Wait. Now what is this? Okay. We could talk after. I don't know about these clitoral drops.”— Halle Berry's reaction highlights the novelty and potential interest in this specific treatment.

Detoxifying your environment

WhatReducing exposure to industrial petrochemicals and xenoestrogens found in everyday products and food.
WhenGradually, by making conscious choices when purchasing food, household cleaners, and personal care products.
DoseOngoing effort to minimize exposure.
For whomEveryone, but particularly women concerned about hormonal health and cancer risk.
WhyXenoestrogens are highly bioactive foreign estrogens that can synergistically increase the risk of cancers (breast, uterine, ovarian) and disrupt hormonal balance. Reducing this burden supports overall health and hormonal regulation.
CaveatsIt's a continuous process; don't expect to eliminate all toxins overnight. Focus on gradual shifts.

The speaker emphasizes the critical importance of detoxifying one's environment to support hormonal health, particularly for women. Industrial petrochemicals, found in makeup, household cleaners, skincare products, and pesticides, act as 'xenoestrogens' – foreign estrogens that are highly bioactive and synergistic. This means their combined effect is far greater than the sum of their individual parts, significantly increasing the risk of breast, uterine, and ovarian cancers. The recommendation is to gradually reduce this burden by choosing organic foods, filtering water, using air filters, and opting for non-toxic skincare and cleaning products. The Environmental Working Group (ewg.org) is cited as a valuable resource for identifying safer products.

Mechanism

Xenoestrogens mimic natural estrogen in the body, binding to estrogen receptors and potentially overstimulating them, leading to increased cancer risk and hormonal dysregulation. By reducing exposure, the body's natural hormonal balance is less disrupted, and the overall toxic load on detoxification pathways is lessened.

I think this is such an important question. And we didn't have time to touch on it, but it's a huge issue, which is industrial petrochemicals, which are in everything from makeup to household cleaners to skincare products Three. Yeah. To our food, to pesticides, are what we call xenoestrogens.

Also said
“And they're not just additive. They're synergistic. So one plus one doesn't equal two. It equals a thousand.”— Explains the potent and amplified effect of xenoestrogens.
“That's why I'm in the board of the environmental working group, and it's a great resource, ewg.org.”— Provides a practical resource for listeners.

Open communication with partners about sexual health during menopause

WhatEngaging in honest and open conversations with male partners about the physical and emotional changes experienced during menopause, particularly regarding sexual health.
WhenAs soon as changes begin or are noticed, to foster understanding and support.
DoseOngoing, as needed.
For whomWomen in perimenopause or menopause who are in a relationship.
WhyTo destigmatize menopause and sexual health issues, prevent relationship breakdown (50% of marriages end during this time), and ensure partners understand and support the woman's experience.
CaveatsMay require courage to initiate, as partners might initially be embarrassed or uncomfortable.

The speaker strongly advocates for open communication between women and their male partners about the realities of menopause, especially concerning sexual health. This is crucial for destigmatizing the topic and preventing relationship issues, as it's noted that 50% of marriages end during this life stage. Women are encouraged to bravely inform their partners about what's happening to their bodies. While men might initially be embarrassed, the speaker suggests they are often receptive and relieved to understand the situation, fostering a sense of shared experience rather than a 'breakdown in their marriage.' This dialogue allows couples to navigate changes together and maintain intimacy.

Mechanism

Open communication fosters empathy and understanding, allowing partners to address challenges together rather than letting them become sources of conflict or distance. It normalizes the experience of menopause, reducing feelings of isolation and shame for the woman and enabling collaborative problem-solving (e.g., using lubricants, exploring different forms of intimacy).

I think as women, we have to start talking to our partners about it. Yeah. That's right. That's how we destigmatize it, and we make it less taboo.

Also said
“We can take all the drops and take all the, you know, vaginal estrogen we want, and we can use all the lubes we want, but we have to start talking because fifty percent of marriages end at this time of life.”— Highlights the high stakes of not communicating and the importance of dialogue beyond physical treatments.
“And I found that when we talk to our partners, talk to men about it, they're very receptive. You know, they're embarrassed at first. They don't wanna talk about it. But when we force them to, I think men are right there.”— Offers encouragement and insight into how partners might react.

Adopting a 'Shiesta' (Menopause Celebration)

WhatCreating a cultural shift where women's entry into menopause is celebrated as a significant life milestone, similar to other rites of passage.
WhenUpon entering menopause.
DoseA celebratory event or period.
For whomAll women entering menopause, supported by their families and communities.
WhyTo change the negative cultural perception of menopause, empower women, and acknowledge their wisdom and role as matriarchs, fostering a sense of agency and self-worth.
CaveatsRequires a significant cultural shift and active participation from women and their families to implement.

Halle Berry proposes a radical cultural shift: celebrating menopause with a 'shiesta.' She argues that just as other life milestones like birthdays, baby showers, and weddings are celebrated, menopause, as a significant transition, deserves similar recognition. This practice aims to change the negative societal perception of menopause, empowering women to embrace this time as one of wisdom and matriarchy, rather than decline. By actively forcing families to celebrate this period, women can reclaim agency over their experience and foster a more positive self-image, aligning with cultures where older women are revered.

Mechanism

By framing menopause as a celebratory event, it challenges the prevailing narrative of decline and loss, replacing it with one of reverence and empowerment. This cultural validation can positively impact women's self-perception, reduce feelings of depression and isolation, and encourage families to support and honor women during this transition, aligning with how other cultures revere older women.

I think as women, we have to start being celebrated when we are in the menopause with a shiesta. A shiesta. A shiesta. Because we deserve it. Right?

Also said
“We are the matriarchs of our family. We are the wisest ones in our family, I'm gonna have to tell you. And in other cultures, we are revered at this time of life. In our country, not so much anymore, and we have to change that.”— Explains the rationale behind the 'shiesta' and contrasts Western views with other cultures.

What's new

Personal practice updates, fresh positions, predictions

4 items

FDA lifts black box warning on Hormone Replacement Therapy (HRT)

10:00

The FDA recently removed the black box warning from hormone replacement therapy, a significant positive development for women's health.

Why this matters: This is a major regulatory change that should encourage more women and doctors to consider HRT, reversing a long-standing negative perception.

Background

A 2002 study, the Women's Health Initiative, incorrectly linked HRT to adverse outcomes like heart attacks, strokes, and increased cancer risk, leading 50 million women to stop hormones overnight and creating a lasting stigma.

The speaker notes that the FDA's decision to lift the black box warning on HRT is one of the best things to happen in women's health. This warning was initially placed due to a flawed 2002 study (Women's Health Initiative) that suggested adverse outcomes from hormone use. This study, despite its problems, caused a mass exodus from HRT, which the speaker calls a 'disaster' for women's health. The lifting of the warning is a step towards correcting this historical error and potentially improving access to effective treatments.

Just last week, there was a big change. You wanna share about it? The FDA lifted that black box warning, and I think that's one of the best things to happen, in women's health.

Also said
“And all of a sudden, boom. Overnight. It was I remember. I think it was 2002 the study came out, and overnight, there were fifty million women that stopped hormones, which was a disaster. Single worst thing, I think, to happen for women's health.”— Highlights the catastrophic impact of the original study and warning.

Hot flashes and brain health

23:00

Hot flashes are not just a discomfort but can have adverse effects on brain health, even if a woman doesn't consciously feel them.

Why this matters: This reframes hot flashes from a mere nuisance to a serious health concern with neurological implications, urging women to take them seriously.

Background

Many people, including healthcare providers, dismiss hot flashes as a normal and benign part of menopause, advising women to 'just deal with it.'

The speaker emphasizes that hot flashes are more than just physical discomfort; they have significant ramifications for brain health. Citing research from Dr. Mackie, it's revealed that women can experience many more hot flashes than they perceive, with adverse effects on the brain occurring with each one. This insight challenges the common dismissal of hot flashes as a minor symptom, underscoring the importance of managing them to protect long-term cognitive function.

And every time you have a hot flash, there's adverse effects to your brain. Right? And so it's not just getting rid of hot flashes so we're we don't feel physical discomfort. It's really trying to minimize the hot flashes to protect our brain.

Also said
“This one woman that she was studying while I was there with her, this woman thought she had high five hot flashes, but in fact, she had 50 hot flashes in a twenty four hour period.”— Illustrates the discrepancy between perceived and actual hot flash frequency and its implications.

Menopause as an 'upgrade' rather than a 'downgrade'

20:00

Menopause should be viewed as an opportunity for women to 'upgrade' to the best version of themselves by adapting their lifestyle and health practices, rather than a period of decline.

Why this matters: This offers a positive reframe of menopause, empowering women to embrace it as a natural transition that can lead to improved well-being with the right support.

Background

Societal narratives often portray aging and menopause as a period of decline, loss, and 'shriveling up,' leading to depression and feelings of being unheard.

Halle Berry shares a powerful perspective on menopause, suggesting that with the right knowledge and actions, it can be an 'upgrade' rather than a 'downgrade.' She recounts feeling depressed and thinking she was 'just getting old' and would 'shrivel up,' but through her journey, she realized that by supporting her changing body with appropriate diet, exercise (like heavy weightlifting instead of excessive cardio), and potentially hormones, she could become a better version of herself. This reframing emphasizes agency and the potential for growth during this life stage.

Personal experience

I felt afraid, and I thought, I'm just getting old. And now I'm going to just shrivel up, and I'm gonna go off to pasture, and nobody's gonna care. That's how I felt very depressed. I felt that alone and, like, that nobody heard my feelings. ... I realized that this new body was the better version of myself. We often think, oh, we're getting older, and we're sort of downgrading, but we're not downgrading. When we know the things to do, we're upgrading. We're spiraling into the best version of ourselves.

We often think, oh, we're getting older, and we're sort of downgrading, but we're not downgrading. When we know the things to do, we're upgrading. We're spiraling into the best version of ourselves.

Also said
“I now needed to lift heavy, heavy weights, and I never did that before.”— Provides a concrete example of a lifestyle change that contributed to her 'upgrade'.

Food racism and health disparities in black and brown women

31:00

Black and brown women suffer exponentially more from health issues, including those related to menopause, due to 'food racism' where the food industry deliberately targeted these populations with unhealthy processed foods.

Why this matters: This highlights a critical social determinant of health, linking systemic issues to specific health outcomes and calling for more research into these disparities.

Background

Historically, African American populations in the 1960s were healthier than white populations, but this trend reversed due to targeted marketing of unhealthy foods.

The speaker points out that black and brown women experience significantly worse health outcomes, including during menopause, a disparity attributed to 'food racism.' This concept describes how the food industry deliberately targeted these communities with processed foods, leading to higher rates of diabetes, kidney failure, hypertension, and cardiovascular disease. This is not a genetic issue but a consequence of systemic targeting, which has profoundly impacted their health compared to historical baselines.

And, also, black and brown women suffer exponentially more. A lot more. Yeah. And I would want I'm curious to know why that is. We need more resources.

Also said
“And then what happened was that they got targeted by the food industry in a very malicious and deliberate way, and they then consumed far more soda, far more junk food, far more processed food.”— Explains the mechanism of 'food racism' and its impact.
“Why? They were thirty percent of the population in New Orleans and Chicago, where we're seventy percent of the COVID deaths. That's why. Because it it's not it's not some genetic abnormality. It's because of our our our embedded I would I I call it kind of food racism.”— Connects historical health disparities to current outcomes and defines 'food racism'.

Recommendations

Products, supplements, and tools mentioned in the episode

1 item

Functional Health (Functional Medicine)

Service

A diagnostic and treatment approach that looks at the root causes of health issues, including hormonal imbalances, by conducting deep diagnostics.

Functional Health, or Functional Medicine, is highlighted as a crucial approach for understanding and treating menopausal symptoms. It involves 'deep diagnostics' to assess hormonal, metabolic, and nutritional status, allowing practitioners to identify underlying patterns of dysfunction. This comprehensive testing helps to understand why hormones like insulin, cortisol, thyroid, and sex hormones might be imbalanced, leading to various symptoms. The goal is to empower individuals with their data to make informed decisions about their health, and platforms like ReSpin can then help women interpret these reports and follow through with protocols.

vs alternatives

Contrasted with conventional medicine's approach, which often fails to identify the root causes of menopausal symptoms and misdiagnoses them.

Personal experience

Halle Berry describes her experience with Functional Health testing: "I just did my function test. You guys sent someone in my house. I swear they took every ounce of blood out of my body. She said, I'm gonna take 17 vials of blood. I said, excuse me? What? You wanna know everything. She said, yeah. That's what I'm doing. But you know what? Thank God she did because I learned so much."

And, you know, with Functional Health, we do deep diagnostics that help them and understand where they are hormonally, where they are metabolically, where they are nutritionally, and you can start to see the patterns.

Also said
“And that's the beauty of function. I just did my function test. You guys sent someone in my house. I swear they took every ounce of blood out of my body.”— Illustrates the thoroughness of Functional Health diagnostics.
Find Functional
Disclosed sponsorships4speaker disclosed

ReSpin

Service Sponsored · disclosed

A platform founded by Halle Berry to provide comprehensive support for women in perimenopause and menopause.

DisclosureHalle Berry founded ReSpin.

ReSpin is presented as a 'one-stop shop' for women navigating midlife, particularly menopause. It offers a holistic approach, including access to expert doctors specializing in menopausal bodies, the latest scientific information, and coaches who provide guidance and accountability. The platform also fosters a community of women for mutual support and offers a clinic for personalized hormone therapy. Halle Berry describes it as her 'second life passion,' driven by her personal experience of being failed by the medical system.

vs alternatives

Contrasted with the current healthcare system that largely fails women in menopause, offering a comprehensive and supportive alternative.

Personal experience

Halle Berry founded ReSpin out of her personal struggle and misdiagnosis during menopause, stating, "I am determined before I leave this planet to do everything I can to change the life for women, especially in in midlife."

And at ReSpin, we've got, like he said earlier, we've got expert doctors that are experts in our menopausal bodies. We've got access to the latest in science. We've got coaches that will hold your hand, walk you through your function, studies that you get, help you be accountable to your optimal good health.

Also said
“It's a three sixty approach to wellness because we know and if you want hormones, we have a clinic that can also get you on hormones, help you dose those hormones, help you regulate.”— Highlights the comprehensive nature of ReSpin, including hormone therapy access.
Find ReSpin

JoyLux red light therapy device

Tool Sponsored · disclosed

A vaginal device utilizing red light therapy to address vaginal dryness and promote collagen and moisture.

DisclosureHalle Berry partnered with JoyLux and developed a product with them.

Halle Berry discovered the JoyLux red light therapy device as a personal solution for her severe vaginal dryness, a key symptom of perimenopause. She found it effective in building collagen and moisture in the vaginal area. Impressed by its efficacy, she reached out to the company, leading to her involvement and subsequent partnership to develop additional products, such as the 'Let's Spin' lubrication product.

Personal experience

Halle Berry states, "I came across JoyLux and their red light therapy device, which is a vaginal device that sort of helps build collagen, moisture, and you know? And that worked for me. So I reached out to the head of the company, and I said, hey. What is this company? This actually moved my needle. What is this?"

I came across JoyLux and their red light therapy device, which is a vaginal device that sort of helps build collagen, moisture, and you know? And that worked for me.

Find JoyLux

Let's Spin lubrication product

Product Sponsored · disclosed

A clean, hyaluronic acid and aloe vera-based lubrication product designed for sensitive vaginal areas.

DisclosureHalle Berry teamed up with JoyLux to create this product.

Following her positive experience with the JoyLux device, Halle Berry identified a need for a high-quality lubrication product. She collaborated with JoyLux to create 'Let's Spin,' which is formulated with hyaluronic acid and aloe vera, emphasizing its 'clean' and non-sticky properties, making it suitable for women with sensitive skin in that area.

Personal experience

Halle Berry states, "The next product I needed was some sort of lubrication product. So I teamed up with them, and we came up with this, I think, a beautiful product called Let's Spin. It's clean. It's hyaluronic acid aloe vera. It's not sticky."

So I teamed up with them, and we came up with this, I think, a beautiful product called Let's Spin. It's clean. It's hyaluronic acid aloe vera. It's not sticky.

Find Let's

Environmental Working Group (EWG)

Service Sponsored · disclosed

A non-profit organization that investigates and provides information on the safety of products, including household, skincare, cleaning, and food products.

DisclosureMark Hyman is on the board of the Environmental Working Group.

The Environmental Working Group (EWG) is recommended as a crucial resource for individuals looking to reduce their exposure to industrial petrochemicals and xenoestrogens. As a non-profit, EWG investigates and rates various products, helping consumers make informed choices about what they bring into their homes and put on their bodies. Dr. Hyman, being on its board, underscores its credibility and importance in guiding people towards a 'low tox' lifestyle.

That's why I'm in the board of the environmental working group, and it's a great resource, ewg.org. It's a nonprofit that actually investigates all the products that are used in our household products, our skincare products, and our cleaning products, and our food, and everything.

Find Environmental

Notable quotes

Lines worth pulling out — contrarian, specific, or perfectly phrased

7 items
As a physician, I learned almost nothing about menopause in medical school except that it happens. There's sixty million women in America who are in menopause, and they're not being well taken care of by the health care system.
Highlights the systemic failure of medical education and healthcare to address menopause, setting the stage for the entire discussion.
I thought I would skip it. I thought whatever that thing is, I'm gonna skip it. Right? I got myself off insulin. I I knew that food was medicine, and I thought, well, I'm gonna sail through whatever the hell that is. Well, no. We all are gonna face it if we're lucky enough to get there.
Reveals Halle Berry's initial ignorance and denial about menopause, despite her health consciousness, making her experience relatable to many women.
He said, well, this is the worst case of herpes I think I've seen. ... So my guy, Van, is downstairs in the car because he had driven me to the doctor's office. I get in the car and I'm looking at him and I'm like, hey, so, you got herpes?
A dramatic and humorous anecdote that powerfully illustrates the severe misdiagnosis and lack of knowledge surrounding menopausal symptoms, even by experienced doctors.
And I said, then what is it? And he said, I don't know. And I thought, how can you not know? You're the doctor. You don't know what this is? And he said, I truly don't. And that's all he said, and he hung up the phone.
This quote is the turning point for Halle Berry, exposing the profound ignorance of the medical system regarding menopause and motivating her advocacy.
But what you said was bio identical, meaning it's what nature made. You can't patent what nature made like a vitamin or a hormone. And so it's cheap, and it it's not gonna make them money, and so they're not gonna do big studies on this.
Explains the economic disincentive for pharmaceutical companies to research and promote bioidentical hormones, highlighting a systemic barrier to better women's health.
Premarin increases the risk of inflammation. It causes high triglycerides. It increase cancer risk. It's pregnant mare's urine. That's what it stands for. Pregnant mare's urine. Premarin. It's come that's how they get it.
Reveals the shocking origin and negative effects of a commonly prescribed synthetic hormone, underscoring the need for safer alternatives.
We have to change our ticker tape. We have to have agency over this time of our life, and we have to force, and I do say this, force our family to celebrate us. Just like we have now understand that we celebrate our children with their bar mitzvahs and their bat mitzvahs. We have 16 birthdays. We have baby showers and wedding showers, like, you know, bachelorette parties. We celebrate these milestone times in our life. I think as women, we have to start being celebrated when we are in the menopause with a shiesta.
A powerful call to action for women to reclaim agency over menopause and demand societal celebration, introducing the concept of a 'shiesta'.

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Topics covered

menopause neglectperimenopause symptomsvaginal drynessmedical misdiagnosisherpes misdiagnosishealthcare system failurehormone replacement therapy (hrt)bioidentical hormonespremarinproverawomen's health initiativefda black box warningmenopause symptomsdry eyesdry mouthsjogren's diseasebrain fognight sweatssleep deprivationdepression
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