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Episode
Sleep 9 Hours Straight - Best and Worst Nighttime Routines (ranked by science)
~73 min
Episode Brief·YouTube

Sleep 9 Hours Straight - Best and Worst Nighttime Routines (ranked by science)

Thomas DeLauer
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TL;DR

The four things you'd lose by not watching

4 items

TL;DR

The four things you'd lose by not watching

4 items
1

Magnesium (especially glycinate or threonate) and Glycine (3g before bed) are highly effective for improving sleep quality and duration, rated as "sleep savant" strategies.

2

Sauna use before bed, followed by rapid cooling, significantly enhances sleep quality by promoting parasympathetic activity and lymphatic flushing, also rated as "sleep savant."

3

Blue light blocking is less critical than overall light reduction; red light exposure around sunset is more beneficial for sleep signaling.

4

Avoid carbs directly before bed due to potential secondary glucose spikes that disrupt sleep; however, a small amount of honey can help with silent acid reflux.

Protocols

Concrete recipes — what, when, how much, and why

9 items

Magnesium Supplementation for Sleep

WhatTake magnesium, specifically magnesium threonate for a busy brain or magnesium glycinate for general sleep, or magnesium malate for general body relaxation.
Dose400-500mg of magnesium malate (speaker's personal dose).
For whomAnyone struggling with sleep, especially those with a 'busy brain' (threonate) or needing general relaxation (glycinate/malate).
WhyMagnesium acts as a GABA agonist, triggering GABA receptors to promote calming and relaxation. It also reduces excitability in the nervous system by acting as an NMDA agonist.

The speaker rates magnesium as a 'sleep savant' strategy, indicating its high effectiveness. He explains that magnesium's role as a GABA agonist helps trigger the brain's calming inhibitory neurotransmitter, GABA, leading to relaxation. It also functions as an NMDA agonist, reducing overall nervous system excitability. Specific forms are recommended for different needs: magnesium threonate for those with an overactive mind, magnesium glycinate for general sleep improvement, and magnesium malate for broader body relaxation. He personally uses magnesium malate as part of his sleep stack.

Mechanism

Magnesium is a GABA agonist, meaning it activates GABA receptors. GABA (gamma-aminobutyric acid) is the primary inhibitory neurotransmitter in the brain, responsible for calming and relaxation. By enhancing GABA's effects, magnesium helps the brain relax. Additionally, magnesium acts as an NMDA agonist, which further reduces neuronal excitability in the nervous system, contributing to an overall calming effect. Different forms of magnesium target different aspects: threonate crosses the blood-brain barrier more effectively for cognitive effects, while glycinate and malate offer broader relaxation.

Personal experience

I take 400 to 500 milligrams of magnesium malate.

Magnesium is a GABA agonist which means that it actually triggers GABA to be your GABA receptor to essentially be triggered.

Also said
“Different kinds of magnesium like magnesium 3 and 8 cross through the bloodb brain barrier and impact this even more. So if you have a busy brain, magnesium 3 and8 is good. If you just need general sleep, magnesium glycinate is good. If you need general body relaxation, D magnesium melee is the way to go.”— Details specific types of magnesium and their targeted benefits.

Glycine Supplementation for Sleep

WhatTake glycine as an inhibitory neurotransmitter.
WhenBefore bed.
Dose3 grams.
For whomAnyone having a hard time sleeping through the night, especially those who wake up to urinate.
WhyGlycine is an inhibitory neurotransmitter that calms the central nervous system, lowers body temperature, and affects NMDA receptors, promoting relaxation and deeper sleep. It also helps reduce nighttime urination.

The speaker highly recommends glycine, rating it as a 'sleep savant' strategy alongside magnesium. He explains that glycine is an inhibitory neurotransmitter that directly calms both the central nervous system and the body. A key mechanism is its ability to lower core body temperature, which is beneficial for initiating and maintaining sleep. It also interacts with NMDA receptors to further calm the brain. He cites a study from 'Sleep and Biological Rhythms' where 3 grams of glycine significantly improved sleep, confirmed by polysomnography. An unexpected benefit is its ability to calm the bladder, reducing nighttime awakenings for urination, thus helping individuals sleep 8 hours straight.

Mechanism

Glycine functions as an inhibitory neurotransmitter, directly affecting the central nervous system to induce relaxation. It also helps lower core body temperature, which is conducive to sleep. Furthermore, glycine binds to NMDA receptors, contributing to a calming effect at both brain and general body levels. A study published in 'Sleep and Biological Rhythms' showed that 3 grams of glycine significantly improved sleep quality, as measured by polysomnography. An additional benefit is its ability to calm the bladder, reducing the need to urinate during the night.

Personal experience

About three times a week I'll take glycine.

Straight up, just three grams of this stuff can be super effective. It lowers your body temperature, so it makes your body feel cool.

Also said
“There was a study that was published in sleep and biological rhythms that gave subjects 3 g of glycine. And they actually used polyomnography to actually look at their sleep, and they saw they sleep significantly better.”— Provides scientific backing for glycine's efficacy.
“It also has a wild effect on the bladder where it can calm the bladder down and make you not have to pee a bunch in the middle of the night.”— Highlights an additional, practical benefit for sleep duration.

Sauna Use with Cold Plunge for Sleep

WhatUse a sauna followed by rapid cooling (e.g., a cold plunge or cool shower).
WhenBefore bed.
Dose15-20 minutes in a high-heat sauna.
For whomAnyone looking to significantly improve sleep quality and the restorative effects of sleep.
WhyThe rapid cooling after sauna induces a massive parasympathetic response, promoting a calm state and lower body temperature. It also increases lymphatic and cerebral spinal fluid flushing in the brain, enhancing sleep's restorative effects.
CaveatsIf a sauna is unavailable, a hot bath can provide a similar effect.

The speaker rates sauna use with rapid cooling as a 'sleep savant' strategy, despite its initial counterintuitive nature (heating the body). He explains that while a sauna initially increases adrenaline, the key is the rapid cooling that follows. This rapid temperature drop triggers a massive parasympathetic response, shifting the body into a calm, relaxed state and lowering core body temperature, both ideal for sleep. He also highlights a lesser-known benefit: saunas increase the flushing of the lymphatic system and cerebral spinal fluid in the brain. This process is thought to enhance the restorative effects of sleep, potentially making even shorter sleep durations more effective. He personally finds it indispensable and suggests a hot bath as an alternative if a sauna isn't accessible.

Mechanism

While saunas initially increase adrenaline, the subsequent rapid cooling (e.g., cold plunge) triggers a strong parasympathetic nervous system response. This shift from sympathetic (fight or flight) to parasympathetic (rest and digest) promotes deep relaxation and lowers core body temperature, both crucial for sleep. Additionally, sauna use has been found to increase the flushing of the lymphatic system and cerebral spinal fluid in the brain, which is believed to enhance the brain's detoxification and restorative processes during sleep, potentially making sleep more efficient even if duration is shorter.

Personal experience

I don't think I would want to live without this one anymore. I will go meditate for 15 or 20 minutes in a high heat sauna, and then I'll go jump in the swimming pool where I just basically not getting a cold plunge, but I'm just rapidly cooling my body down.

But it's actually a little bit different because when you heat your body like that to an extreme and then you step out, you have a rapid cooling effect that has a massive parasympathetic effect.

Also said
“But it does one other interesting thing that we didn't know is that it increases the flushing of the lymphatic system and cerebral spinal fluid to the brain which means that you're getting more effect from your sleep even if you sleep for less amount of time.”— Explains the unique benefit of enhanced brain detoxification during sleep.

Grounding/Earthing for Cortisol Regulation

WhatStand barefoot on grass or concrete.
WhenFor 5-10 minutes, ideally when cortisol rhythms are disrupted (e.g., low in morning, high in evening).
Dose5-10 minutes.
For whomAnyone struggling with disrupted cortisol rhythms, feeling wired at night or tired in the morning.
WhyGrounding helps reset the body's 24-hour cortisol rhythms, which can be out of sync, leading to being 'wired at night and tired in the morning.'
CaveatsMay seem unusual or 'weird' to others.

The speaker acknowledges that grounding might seem unusual but asserts its effectiveness for sleep. He cites a study published in 'Alternative and Complementary Medicine' which found that standing barefoot on grass or concrete for 5-10 minutes can reset the body's 24-hour cortisol rhythms. This is crucial because an inverted cortisol curve (low in the morning, high in the evening) leads to feeling wired at night and tired in the morning, severely disrupting sleep. By re-establishing a healthy cortisol rhythm, grounding helps the body naturally prepare for sleep. He rates it as 'out like a light,' indicating significant benefit.

Mechanism

A study in the journal 'Alternative and Complementary Medicine' found that grounding (standing barefoot on conductive surfaces like grass or concrete) can reset the body's natural 24-hour cortisol rhythms. When cortisol is dysregulated (e.g., low in the morning and high in the evening), it disrupts the natural sleep-wake cycle, causing difficulty sleeping at night and fatigue in the morning. Grounding helps to re-establish the proper diurnal cortisol curve, promoting a more balanced hormonal state conducive to sleep.

There was a study published in the journal Alternative and Complimentary Medicine where they had people go out and ground and they found that if they stood out in grass or concrete, it would actually reset their 24-hour cortisol rhythms.

Also said
“This is really important because when our cortisol is out of whack in the morning, like it's low in the morning and high in the evening, that throws off our entire scale where we are wired at night and tired in the morning.”— Explains the physiological impact of disrupted cortisol rhythms on sleep.

Tart Cherry Juice for Sleep

WhatConsume tart cherry juice.
WhenA couple of hours before bed.
DoseApproximately 1/4 cup.
For whomIndividuals seeking natural sleep support, particularly those who might benefit from increased melatonin and tryptophan availability.
WhyTart cherry juice contains pro-anthocyanidins that slow tryptophan breakdown, increasing its availability for serotonin and melatonin production. It also provides a natural, low dose of melatonin.
CaveatsMust be consumed a couple of hours before bed to avoid the negative effects of carbs right before sleep.

The speaker rates tart cherry juice as 'out like a light' for its sleep benefits. He explains that it contains pro-anthocyanidins, which slow down the breakdown of tryptophan, making more of it available to convert into serotonin and melatonin—both essential for sleep. Furthermore, tart cherry juice is a rare natural source of low-dose melatonin itself. However, he notes a crucial caveat: due to its carbohydrate content, it should be consumed a couple of hours before bed to avoid the negative effects of carbs taken too close to sleep. A small dose, around 1/4 cup, is sufficient.

Mechanism

Tart cherry juice contains pro-anthocyanidins, which inhibit the breakdown of tryptophan. This increases the availability of tryptophan, a precursor to serotonin and melatonin, thereby promoting their production. Additionally, tart cherry juice is one of the few natural sources of low-dose melatonin, directly contributing to sleep regulation. The timing is crucial: consuming it a few hours before bed allows the active compounds to work without the potential sleep disruption caused by the juice's carbohydrate content if taken too close to bedtime.

This means you have more tryptophan available to convert into serotonin, more tryptophan available to convert into melatonin and ultimately help you sleep. Tart cherry juice is also one of very few natural sources of very lowdose melatonin.

Also said
“But the thing is it comes at a cost. you have to have some carbs with it. So, the trick is with tart cherry juice, you want to have it a couple hours before bed.”— Explains the timing and carbohydrate consideration.

Evening Meal Timing and Carbohydrate Allocation

WhatEat dinner early and allocate carbohydrates to this meal.
WhenDinner, at least 3 hours before bed.
For whomAnyone looking to optimize their evening routine for better sleep.
WhyEating early allows for proper rest and digestion. Allocating carbohydrates to the evening meal can help calm and relax the body by increasing serotonin levels, without causing sleep disruption if timed correctly.
CaveatsEnsure the meal is at least 3 hours before bed to avoid negative effects of carbs right before sleep.

As part of his personal evening routine, the speaker eats dinner early, primarily because he has young children, but also to allow ample time for digestion before sleep. He strategically allocates his daily carbohydrate intake to this evening meal. His rationale is that these carbohydrates can help calm and relax the body by increasing serotonin levels, which is beneficial for sleep. However, he stresses the importance of timing, ensuring this meal is consumed at least three hours before bedtime to prevent any potential sleep disruption from a late-night glucose spike.

Mechanism

Eating dinner early provides sufficient time for the body to digest food before sleep, promoting a 'rest and digest' state. Carbohydrates, when consumed at this time, can help increase serotonin levels, a precursor to melatonin, which aids in relaxation and sleep initiation. The crucial aspect is the timing; consuming carbs too close to bedtime can lead to a secondary glucose spike that disrupts sleep, as discussed earlier. By eating them at least 3 hours before bed, the body can process them and utilize their calming effects without the negative rebound.

Personal experience

I come home, I have dinner pretty early because I like to rest and digest after my meal as much as I can. And I have young kids, so we eat dinner early. Okay. And what I'll do is I'll typically allocate my carbohydrates to that meal, my last meal of the day. That way, I'm getting carbohydrates that are going to calm me down, relax me, increase my serotonin levels, but 3 hours at least before bed.

That way, I'm getting carbohydrates that are going to calm me down, relax me, increase my serotonin levels, but 3 hours at least before bed.

Box Breathing for Relaxation

WhatPractice box breathing.
WhenBefore bed.
DoseInhale for 6 counts, hold for 6, exhale for 8, hold for 6 (6-6-8-6 pattern).
For whomAnyone seeking to calm their mind before sleep.
WhyThis specific breathing pattern helps to shift the brain into a more relaxed state.

The speaker includes box breathing as a crucial part of his personal sleep routine. He uses a specific pattern: inhale for six counts, hold for six, exhale for eight, and hold for six (6-6-8-6). He finds this technique highly effective in transitioning his brain into a more relaxed gear, preparing him for sleep. This practice is a direct method for engaging the parasympathetic nervous system and calming the mind.

Mechanism

Box breathing, with its specific inhale, hold, exhale, and hold pattern, is a technique known to activate the parasympathetic nervous system. By consciously controlling the breath, it helps to slow heart rate, reduce stress hormones, and promote a state of relaxation, effectively shifting the brain's activity towards a calmer, sleep-ready state.

Personal experience

But one of the more important things I do box breathing before I go to bed. So I'll breathe in for six, hold for six, exhale for eight, hold for six. So six, six, eight, six. and that seems to really kick my brain into a more relaxed gear.

So I'll breathe in for six, hold for six, exhale for eight, hold for six. So six, six, eight, six. and that seems to really kick my brain into a more relaxed gear.

Water Intake Restriction Before Bed

WhatLimit water intake.
WhenAfter 6 PM, except for small sips with supplements.
DoseOnly 4-6 ounces with electrolytes if needed.
For whomAnyone who frequently wakes up at night to use the restroom.
WhyTo prevent waking up to urinate during the night, ensuring uninterrupted sleep.

To avoid waking up during the night for bathroom breaks, the speaker restricts his water intake after 6 PM. He makes an exception for a small amount (4-6 ounces) of water when taking his potassium electrolytes, ensuring he stays hydrated without overfilling his bladder before sleep. This practice is aimed at preventing sleep interruptions caused by nocturia.

Mechanism

Restricting fluid intake in the hours leading up to bedtime reduces the volume of urine produced by the kidneys, thereby minimizing the urge to urinate during the night. This helps prevent sleep fragmentation caused by nocturnal bathroom trips, allowing for more continuous and restorative sleep.

Personal experience

I cut out my water after about 6:00 p.m. if possible except for little sips and that maybe little 4 to 6 ounces along with my potassium electrolytes.

I cut out my water after about 6:00 p.m. if possible except for little sips and that maybe little 4 to 6 ounces along with my potassium electrolytes.

Avoiding Intense Conversations and Stressful Emails Before Bed

WhatRefrain from engaging in intense discussions or checking stressful communications.
WhenBefore bed.
For whomEveryone.
WhyTo prevent mental arousal and stress that can interfere with the ability to relax and fall asleep.

The speaker emphasizes the importance of avoiding mentally stimulating or stressful activities right before bed. He specifically mentions refraining from intense conversations and checking stressful emails. His rationale is that these activities can activate the mind and body, making it difficult to relax and fall asleep. This practice complements his other wind-down routines by minimizing external stressors that could disrupt the transition to sleep.

Mechanism

Engaging in intense conversations or dealing with stressful emails before bed can activate the sympathetic nervous system, increasing alertness and stress hormones like cortisol. This makes it difficult for the mind and body to transition into a relaxed state conducive to sleep. By avoiding such activities, the brain can wind down more effectively, promoting the parasympathetic 'rest and digest' state necessary for sleep.

Personal experience

I also don't have any intense conversations before bed or deal with any stressful emails.

I also don't have any intense conversations before bed or deal with any stressful emails.

What's new

Personal practice updates, fresh positions, predictions

6 items

Blue Light Blocking vs. Overall Light Reduction

0:50

Blue light blocking is less impactful than generally reducing overall light exposure (lumens) before bed. Red light exposure around sunset is more beneficial for sleep signaling.

Why this matters: Challenges the common emphasis on blue light blocking by highlighting the greater importance of overall light intensity and introduces the benefit of red light.

Background

The common understanding is that blue light disrupts sleep by signaling wakefulness to the suprachiasmatic nucleus. Many people use blue light blocking glasses or filters.

While blue light does signal wakefulness, the speaker argues that the sheer intensity of light (lumens) is a more significant factor in disrupting sleep than the blue spectrum itself. The reason blue light gets so much attention is because modern devices emit it, and we spend a lot of time in front of them. A more effective strategy is to reduce the brightness of screens and room lighting. Furthermore, incorporating red light exposure around sunset is suggested as a superior method, as red light can signal to the body that it has received sufficient 'anti-inflammatory light signaling' for the day, aligning with natural light cycles.

But if you look hard at the science, you find blue light is important, but what's more important is the level of light that you're exposed to.

Also said
“So, at the end of the day, like cutting out blue light is really important, but it's almost a better strategy to just reduce the brightness on your phone, reduce the brightness in your room, and actually focusing on adding red light is better because red light can actually impact your eyes to a certain level and tell your body that you've had enough light for the day and that you've gotten the adequate amount of sort of anti-inflammatory light signaling, right?”— Explains the alternative strategy of reducing overall brightness and the benefit of red light.

Direct GABA Supplementation Ineffectiveness

3:00

Taking GABA supplements directly is largely ineffective for sleep because GABA is a large molecule with low bioavailability and cannot easily cross the blood-brain barrier.

Why this matters: Contradicts the intuitive idea that supplementing GABA would directly increase brain GABA levels for sleep.

Background

GABA is a known calming neurotransmitter, and many supplements are marketed to increase its levels for relaxation and sleep.

The speaker explains that while GABA is the primary inhibitory neurotransmitter responsible for calming the brain, direct supplementation of GABA is ineffective for sleep because it's a large molecule that struggles to cross the blood-brain barrier. The only exception would be if an individual has a 'leaky brain,' which indicates more severe health issues. While it might have some effect on the enteric nervous system, potentially calming the gut, it won't directly impact brain-level sleep. Alternatives like magnolia bark or honokiol are mentioned as more bioavailable forms that influence the GABAergic system, but even these can lead to dependency if overused.

Thing is, GABA is a large molecule and GABA has low bioavailability. GABA cannot cross through the bloodb brain barrier unless you actually have a leaky brain which then you have bigger things to deal with.

Also said
“But you may want to go with something like magnolia bark or honky which is a more bioavailable form of GABA.”— Suggests more bioavailable alternatives to direct GABA.

Carbohydrates Before Bed for Sleep

6:00

Eating carbohydrates directly before bed is generally counterproductive for sleep, as the initial sleep-inducing hypoglycemia is often followed by a secondary glucose spike that disrupts sleep later in the night.

Why this matters: Debunks the common belief that carbs before bed universally aid sleep, explaining the physiological mechanism of disruption.

Background

Some people consume carbohydrates before bed, believing it helps them fall asleep due to an initial drop in blood sugar.

The speaker acknowledges that consuming carbs before bed can initially induce sleep by causing a drop into hypoglycemia. However, he cites studies showing that this is often followed by a second glucose spike later in the night, which can disrupt sleep. Therefore, for general sleep improvement, he advises against it, rating it as 'grasping for straws.' An exception is made for a small amount of honey (half a tablespoon) for individuals experiencing 'silent reflux,' as it can coat the throat and alleviate symptoms that might otherwise wake them.

You fall asleep for the first 4 hours and then the studies show you get that second glucose spike that happens from carbs.

Also said
“However, there is some interesting stuff with like 1/ half a tablespoon or so of honey, but that's mainly for people that deal with like uh what's called a different kind of acid reflux. It's like an acid reflux that silent reflux that comes up in your throat and wakes people up.”— Provides a specific exception for honey and explains its mechanism for silent reflux.

Tryptophan Supplementation Effectiveness

7:00

Tryptophan supplements are often ineffective for sleep if taken with other food, as it must compete with other amino acids for absorption into the brain.

Why this matters: Explains a critical caveat for tryptophan's efficacy, which is often overlooked in general recommendations.

Background

Tryptophan is known as a precursor to serotonin and melatonin, leading to the belief that supplementing it will directly improve sleep.

Tryptophan is a precursor to serotonin and melatonin, which are crucial for sleep. However, the speaker explains that tryptophan is an amino acid and must compete with other amino acids from food for transport across the blood-brain barrier. To be effective, tryptophan should be taken in isolation, without other food, to ensure it has an 'unopposed' chance to reach the brain. If taken with meals, its efficacy is significantly reduced, leading to 'foggy' sleep at best.

Problem is, it has to compete with other amino acids. It has to compete with proteins that you get from your food. So, if you take in tryptophan, you really should be taking it in by itself without other food so that it's unopposed.

Exercise Before Bed and Sleep

7:50

Exercising heavily before bed is detrimental to sleep, as the adrenaline and cortisol increase from the workout override any potential sleep pressure built from adenosine.

Why this matters: Clarifies why a seemingly logical approach (building tiredness) actually backfires due to hormonal responses.

Background

The idea that physical exhaustion (adenosine pressure) leads to better sleep is common, suggesting exercise before bed might be beneficial.

The speaker addresses the common misconception that exercising before bed would improve sleep by building 'adenosine pressure' (the molecule that signals tiredness). While adenosine does build up with physical activity, the hormonal response to intense exercise—specifically, increased adrenaline and cortisol—overrides this effect. These stress hormones activate the body, making it harder to fall asleep and achieve quality rest. Therefore, heavy exercise before bed is considered more harmful than good for sleep.

However, something overrides that. The adrenaline from a workout and the cortisol increase from a workout actually overrides the entire system of getting that benefit, right?

Melatonin as a Hormone vs. Supplement

13:00

Melatonin is a hormone, not just a supplement, and while effective for sleep, its use can lead to perceived dependency, making it difficult to stop once started.

Why this matters: Highlights the hormonal nature of melatonin and the practical implications of its use, including potential dependency, despite scientific claims.

Background

Melatonin is widely used as a sleep aid, often treated as a simple supplement.

The speaker emphasizes that melatonin is a hormone, not merely a supplement, which changes the perspective on its use. While it effectively improves sleep and sleep scores, he expresses personal reservations about continuous use due to the anecdotal experience of dependency, where individuals find it hard to sleep without it once they start. He notes that scientific research may not show dependency, but real-world experience suggests otherwise. He personally uses it strategically for travel or when sick children disrupt his sleep, rather than as a daily aid. He also points out that melatonin is not available in all countries.

Personal experience

I don't feel like for me it's something I would want to be hooked on. However, I will use it when I travel. I will use it somewhat frequently if I need it or if the kids are sick and I feel like I need to get a good rest to make sure I don't pick up what they've got, I'll use it.

Melatonin is a hormone and I have to be very frank. I've talked to lots of different people on this and have different get different opinions.

Also said
“However, anecdote shows that when people take it and they stop taking it, they have a hard time falling asleep.”— Explains the basis for the perceived dependency.

Recommendations

Products, supplements, and tools mentioned in the episode

8 items

Magnesium Threonate

Supplement

Recommended for individuals with a 'busy brain' due to its ability to cross the blood-brain barrier more effectively.

vs alternatives

Compared to magnesium glycinate for general sleep and magnesium malate for general body relaxation.

So if you have a busy brain, magnesium 3 and8 is good.

Find Magnesium

Magnesium Glycinate

Supplement

Recommended for general sleep improvement.

vs alternatives

Compared to magnesium threonate for a busy brain and magnesium malate for general body relaxation.

Personal experience

I'll oftentimes take magnesium glycinate too.

If you just need general sleep, magnesium glycinate is good.

Find Magnesium

Magnesium Malate

Supplement

Recommended for general body relaxation.

vs alternatives

Compared to magnesium threonate for a busy brain and magnesium glycinate for general sleep.

Personal experience

I will take 4 to 500 milligrams of dag magnesium mealate.

If you need general body relaxation, D magnesium melee is the way to go.

Find Magnesium

Magnolia Bark / Honokiol

Supplement

Suggested as more bioavailable alternatives to direct GABA supplementation for influencing the GABAergic system.

vs alternatives

Presented as superior to straight GABA supplements due to better bioavailability.

But you may want to go with something like magnolia bark or honky which is a more bioavailable form of GABA.

Find Magnolia

Glycine

Supplement

A highly effective inhibitory neurotransmitter for sleep, especially for sleeping through the night.

Glycine is presented as a 'sleep savant' supplement due to its significant impact on sleep quality. It acts as an inhibitory neurotransmitter, calming the central nervous system. A key benefit is its ability to lower body temperature, which is conducive to sleep. It also interacts with NMDA receptors to promote relaxation. The speaker cites a study showing that 3 grams of glycine improved sleep quality and duration, and notes its additional benefit of calming the bladder to reduce nighttime urination.

vs alternatives

Ranked alongside magnesium as a 'must' for those struggling with sleep.

Personal experience

About three times a week I'll take glycine.

Straight up, just three grams of this stuff can be super effective. It lowers your body temperature, so it makes your body feel cool.

Find Glycine

L-Theanine

Supplement

Can tilt brain waves to an alpha state for potential sleep improvement, but requires a higher dose.

Personal experience

I will take 400 milligrams of theine.

It tilts your brain waves to more of the alpha state, which makes it so you can potentially sleep better. But the thing is is that you really need a higher dose to get the effect that people really want. So 400 600 millig really.

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5-HTP

Supplement

Used when feeling stressed out.

Personal experience

Sometimes I will take a 5http if I feel like I've been a little too stressed out. 5http is something that is I'll usually take like a 50 milligram dose.

Sometimes I will take a 5http if I feel like I've been a little too stressed out.

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Cortisepid

Supplement

Part of the speaker's personal sleep stack.

Personal experience

I will take something called cortisepid sort of my sleep stack.

I will take something called cortisepid sort of my sleep stack.

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Disclosed sponsorships3speaker disclosed

Seed Daily Synbiotic

Supplement Sponsored · disclosed

A clinically backed probiotic recommended for gut health, which is linked to brain health and sleep.

DisclosureThe speaker provides a link for 25% off, indicating a promotional affiliation.

The speaker highly recommends Seed Daily Synbiotic, stating it's the only probiotic he would personally use. He emphasizes its clinical backing, distinguishing it from generic options. He explains that a healthy gut microbiome, supported by this probiotic, can remodel and recolonize gut bacteria, leading to better absorption, improved fatty acid oxidation, and glucose metabolism. This overall gut health is crucial for sleep, as gut and brain health are interconnected, especially concerning issues like leaky gut and leaky brain.

vs alternatives

Described as a 'clinically backed probiotic' unlike 'fly by night' ones found in any store.

Personal experience

It's the one that I generally recommend or always recommend. It's called Seed... It's literally the only one that I would use.

This is a clinically backed probiotic. It's not a fly by night one that you pick up at any store. This is very different and it's a very clinically dosed and very very clinically effective.

Also said
“And if you're focusing on sleep, you got to be focusing on gut, too, cuz they go hand in hand.”— Highlights the connection between gut health and sleep.
Find Seed

Tromune

Product Sponsored · disclosed

A product the speaker takes from Trocriptions as part of his sleep stack.

DisclosureProduct from 'Trocriptions', a brand the speaker mentions.

Personal experience

I take a product from Trocriptions called Tromune.

I take a product from Trocriptions called Tromune.

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Troll Calm

Product Sponsored · disclosed

A product the speaker takes during the day from Trocriptions.

DisclosureProduct from 'Trocriptions', a brand the speaker mentions.

Personal experience

I also will take Troll Calm during the day.

I also will take Troll Calm during the day.

Find Troll

Notable quotes

Lines worth pulling out — contrarian, specific, or perfectly phrased

6 items
Melatonin works for falling asleep, but Melatonin works for falling asleep, but Melatonin works for falling asleep, but there's other things that are actually there's other things that are actually there's other things that are actually even better.
Sets the stage for the video's premise: exploring sleep aids beyond melatonin, implying melatonin isn't the ultimate solution.
If you're eating well, if you're training well and you're just not putting it all together, like you're not getting the results, it's a very good chance it has to do with the quality of your sleep. It's everything. It's the foundation.
Emphasizes the foundational importance of sleep, positioning it as a critical factor even when other health aspects are optimized.
But if you look hard at the science, you find blue light is important, but what's more important is the level of light that you're exposed to.
Challenges a widely accepted belief about blue light, suggesting a deeper, more nuanced scientific understanding.
Thing is, GABA is a large molecule and GABA has low bioavailability. GABA cannot cross through the bloodb brain barrier unless you actually have a leaky brain which then you have bigger things to deal with.
Provides a clear, scientific reason why a common sleep supplement (GABA) is ineffective, debunking a popular misconception.
You fall asleep for the first 4 hours and then the studies show you get that second glucose spike that happens from carbs.
Explains the specific mechanism by which carbs before bed can disrupt sleep, even if they initially help.
Melatonin is a hormone and I have to be very frank. I've talked to lots of different people on this and have different get different opinions.
Highlights the distinction between melatonin as a hormone versus a simple supplement and acknowledges differing expert opinions, adding nuance to its discussion.

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Topics covered

melatonintart cherry juicesleep qualityblue light blockingsuprachiasmatic nucleusred lightmagnesiumgabanmda agonistmagnesium threonatemagnesium glycinatemagnesium malategaba supplementsblood brain barrierleaky brainmagnolia barkhonokiolgut healthprobioticseed daily symbiotic
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One email a week: the sharpest new disagreements and protocols from the library. No spam, unsubscribe anytime.

Educational summary of the cited expert source — not medical advice. Open the source recording linked above and consult a qualified physician before acting on any protocol.